In two interconnected stories Robert, a jaded middle-aged New Yorker, goes to Serbia to make quick cash by marrying someone for U.S. immigration papers. The plan goes awry when the promised cash never arrives. At the same time, a young Serbian immigrant named Branko struggles in a never forgiving New York, desperately trying to bring his girlfriend from Serbia to USA.

A deadly infection breaks out in Manhattan, causing humans to devolve into blood-thirsty rat creatures. Six recently evicted tenants must survive the night and protect their downtown apartment building as the city quickly spirals out of control.

The rise and fall of salsa singer, Héctor Lavoe (1946-1993), as told from the perspective of his wife Puchi, who looks back from 2002. In the early 1960s, Héctor arrives in New York from Ponce, Puerto Rico. Success comes quickly. "The more he grew as an artist," Puchi says, "the more he sank as a person." It's a tale of talent - creating salsa with Willie Colón, with the Fania All Stars, and as a soloist - and a story of disintegration - fueled by drugs, alcohol, partying, and depression. Puchi's voice - proud and querulous - dominates off-stage as Héctor's does on.